10-hydroxy-2-decenoic acid (10-HDA)

General Description

Product Name: 10-hydroxy-2-decenoic acid

Synonyms: Royal Jelly Acid, 10-HDA, 10-hydroxy-delta 2-decenoic acid, (E)-1 0-hydroxy-2-decenoic acid, Trans 10-hydroxy-2-decenoic acid.

Molecular Structure:


Molecular Formula: C10H1803
CAS: 14113-05-4
Molecular Weight: 186.25

Brief introduction 

10-Hydroxy-2-Decenoic Acid is a special active substance which exists only in royal jelly in the nature. It is also called 10-HDA or royal jelly acid. The content of 10-HDA in royal jelly is usually around 1.5%-2.0%. Since it has the function of anticancer, skin care and antibacterial effect etc., it can be added to health food or cosmetics as an active ingredient. The content of 10-FIDA in royal jelly is the international standard of the quality of royal jelly and it directly determines the price of royal jelly on the international market.


(1) 10-HDA possesses strong inhibition to the growth of cancer cells, namely transferable AKR Leukemia, TA3 breast cancer, etc. Recent studies show that 10-HDA possesses the effect of immune-regulation and anti-cancer activities.

10-HDA’s strong cancer fighting properties were first witnessed by a study published in Nature in May 1959. The scientists mixed 10-HDA with active tumor cells taken from cancerous mice. They report that an injection of the mixture suppressed mouse leukemia and inhibited the formation of tumors.

These results have been confirmed repeatedly on nearly 1000 mice during a two-year period and show a striking effect: either all the mice die quickly, or all survive. Two groups of mice which received tumor cells plus 10-HDA remained alive and healthy more than 12 months after inoculation, while sister mice which received the same number of tumor cells without 10-HDA died within 12 days.

In other words, the scientists came up with a vaccine that protects mice against leukemia and the subsequent development of related tumors.

(2) 10-HDA has a strong antibacterial property

(3) 10-HDA has skin care, skin whitening and anti-oxidative activity effect

(4) 10-HDA prevents the loss of Leukocyte during the chemical treatment.

(5) 10-HDA has other functions including treatment of AIDS and other immunodeficiency diseases, insulin-like effect for diabetes and Hypertension, Antiulcer effects, and preventive and therapeutic effects on hyperlipidemia.

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